Computational Cell Biology Simulator & In Silico Drug Testing Platform — C++20/Metal, Novak-Tyson CDK ODE, Fick Diffusion, PhysiPKPD Pharmacodynamics

⚛️📈 Create and analyze chemical microkinetic models built from computational chemistry data. Crafted at the @geem-lab.

In-silico PCR, primer design and padlock design for in-situ sequencing

PyPEF – Pythonic Protein Engineering Framework

[Mirror of https://gitlab.braingenix.org/carboncopies/] BrainGenix-NES is a cutting-edge simulation platform for whole brain emulation research and development that supports digitally replicating both form and function of brain tissue. Developed by the Carboncopies Foundation's BrainGenix initiative, it complements the Virtual Brain Platform (VBP).

OpenMandible: An open-source framework for highly realistic numerical modelling of lower mandible physiology

PyPEF – Pythonic Protein Engineering Framework

In-silico PCR amplification on complete genomes

⚛️📈 Create and analyze chemical microkinetic models built from computational chemistry data

An in silico framework for multi-scale modeling and analysis of in vivo neuron-network mechanisms

In silico therapeutic target discovery using network attractors: avoiding pathological phenotypes

Insert genes into genomes to aid synthetic test data generation

Code for our paper at SPIE Medical Imaging 2022: "Toward Perception-based Anticipation of Cortical Breach During K-wire Fixation of the Pelvis"

In-silico data generation package. Easy and consistent generation of example data for chemical/biochemical reaction case studies.

Model 3 HH neurons connected in different motifs and different axonal delays. Compute synchronization between spikes and information flow between them.

REDigest: a Python GUI for In-Silico Restriction Digestion Analysis for Gene or Complete Genome Sequences

Source code and data for reproducing "The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk".

Create a functional connectome from physical connections between cells

Create indexes of simple shapes and find all indexed elements that intersect with a query region.

Ce dépôt présente le premier jumeau numérique biophysique d'un neurone dopaminergique humain pour le criblage pharmacologique in-silico de la maladie de Parkinson. La solution, propulsée par Flask, Three.js, Celery et Docker, modélise la mutation LRRK2 G2019S pour tester des traitements potentiels.